Independent Spirit Award for Best Female Lead winners

Catalina Sandino Moreno
Catalina Sandino Moreno (born April 19, 1981) is a Colombian actress.

Charlize Theron
Charlize Theron is a South African actress and fashion model.

Ellen Page
Ellen Philpotts-Page (born February 21, 1987), known professionally as Ellen Page, is a Canadian actress.

Felicity Huffman
Felicity Kendall Huffman is an American film, stage, and television actress.

Gabourey Sidibe
Gabourey "Gabby" Sidibe is an American actress who made her acting debut in the 2009 film Precious, a role that brought her a nomination for the Academy Award for Best Actress.

Geraldine Page
Geraldine Sue Page (November 22, 1924 – June 13, 1987) was an American actress.

Isabella Rossellini
Isabella Fiorella Elettra Giovanna Rossellini is an Italian actress, filmmaker, author, philanthropist, and model.

Jodie Foster
Jodie Foster (born Alicia Christian Foster; November 19, 1962) is an American actress, film director, and producer.

Julianne Moore
Julianne Moore is a British-American actress and a children's book author.

Melissa Leo
Melissa Chessington Leo is an American actress.

Sally Kirkland
Sally Kirkland (born October 31, 1941) is an American film and television actress.

Shareeka Epps
Shareeka Epps (born July 11, 1989) is an American actress.