SettingsNeurodegenerative disorders
Adrenoleukodystrophy
Adrenoleukodystrophy (ALD, also called Siemerling-Creutzfeldt Disease or Schilder's disease) is a rare, inherited disorder that leads to progressive brain damage, failure of the adre...
Adrenoleukodystrophy (ALD, also called Siemerling-Creutzfeldt Disease or Schilder's disease) is a rare, inherited disorder that leads to progressive brain damage, failure of the adre...
AIDS dementia complex
AIDS dementia complex (ADC; also known as HIV dementia, HIV encephalopathy, HIV-associated dementia and HIV-associated neurocognitive disorder) is a common neurolog...
AIDS dementia complex (ADC; also known as HIV dementia, HIV encephalopathy, HIV-associated dementia and HIV-associated neurocognitive disorder) is a common neurolog...
Alexander disease
Alexander disease is a slowly progressing and fatal neurodegenerative disease.
Alexander disease is a slowly progressing and fatal neurodegenerative disease.
Alpers' disease
Alpers' disease, also called Alpers' syndrome, , progressive sclerosing poliodystrophy, and progressive infantile poliodystrophy, is a progressive degenerative disease of th...
Alpers' disease, also called Alpers' syndrome, , progressive sclerosing poliodystrophy, and progressive infantile poliodystrophy, is a progressive degenerative disease of th...
Alzheimer's disease
Alzheimer's disease, also known in medical literature as Alzheimer disease, is the most common form of dementia.
Alzheimer's disease, also known in medical literature as Alzheimer disease, is the most common form of dementia.
Amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS), also referred to as Lou Gehrig's disease in American English and motor neurone disease in British English, is a form of motor neurone disea...
Amyotrophic lateral sclerosis (ALS), also referred to as Lou Gehrig's disease in American English and motor neurone disease in British English, is a form of motor neurone disea...
Ataxia telangiectasia
Ataxia telangiectasia is a rare, neurodegenerative, inherited disease causing severe disability.
Ataxia telangiectasia is a rare, neurodegenerative, inherited disease causing severe disability.
Batten disease
Batten disease (also known as Spielmeyer-Vogt-Sjögren-Batten disease) is a rare, fatal autosomal recessive neurodegenerative disorder that begins in childhood.
Batten disease (also known as Spielmeyer-Vogt-Sjögren-Batten disease) is a rare, fatal autosomal recessive neurodegenerative disorder that begins in childhood.
Bovine spongiform encephalopathy
Bovine spongiform encephalopathy, commonly known as mad cow disease, is a fatal neurodegenerative disease in cattle that causes a spongy degeneration in the brain and spinal cord.
Bovine spongiform encephalopathy, commonly known as mad cow disease, is a fatal neurodegenerative disease in cattle that causes a spongy degeneration in the brain and spinal cord.
Canavan disease
Canavan disease, also called Canavan-Van Bogaert-Bertrand disease, aspartoacylase deficiency or aminoacylase 2 deficiency, is an autosomal recessive degenerative disorder that ...
Canavan disease, also called Canavan-Van Bogaert-Bertrand disease, aspartoacylase deficiency or aminoacylase 2 deficiency, is an autosomal recessive degenerative disorder that ...
Corticobasal degeneration
Corticobasal degeneration or Corticobasal Ganglionic Degeneration is a rare, progressive neurodegenerative disease involving the cerebral cortex and the basal ganglia.
Corticobasal degeneration or Corticobasal Ganglionic Degeneration is a rare, progressive neurodegenerative disease involving the cerebral cortex and the basal ganglia.
Creutzfeldt-Jakob disease
Creutzfeldt–Jakob disease or CJD (pronounced, "KROITS-felt YA-kob") is a degenerative neurological disorder (brain disease) that is incurable and invariably fatal.
Creutzfeldt–Jakob disease or CJD (pronounced, "KROITS-felt YA-kob") is a degenerative neurological disorder (brain disease) that is incurable and invariably fatal.
Creutzfeldt–Jakob disease
Creutzfeldt–Jakob disease or CJD (pronounced, "KROITS-felt YA-kob") is a degenerative neurological disorder (brain disease) that is incurable and invariably fatal.
Creutzfeldt–Jakob disease or CJD (pronounced, "KROITS-felt YA-kob") is a degenerative neurological disorder (brain disease) that is incurable and invariably fatal.
Dementia with Lewy bodies
Dementia with Lewy bodies, also known under a variety of other names including Lewy body dementia, diffuse Lewy body disease, cortical Lewy body disease, and senile dementia...
Dementia with Lewy bodies, also known under a variety of other names including Lewy body dementia, diffuse Lewy body disease, cortical Lewy body disease, and senile dementia...
Diagnostic criteria for MS
Schumacher criteria were the first internationally recognized criteria for diagnosis, and introduced concepts still in use, as CDMS.
Schumacher criteria were the first internationally recognized criteria for diagnosis, and introduced concepts still in use, as CDMS.
Diffuse myelinoclastic sclerosis
Diffuse myelinoclastic sclerosis, sometimes referred to as "Schilder's disease", is a very infrequent neurodegenerative disease that presents clinically as pseudotumoural demyelinating lesions, ...
Diffuse myelinoclastic sclerosis, sometimes referred to as "Schilder's disease", is a very infrequent neurodegenerative disease that presents clinically as pseudotumoural demyelinating lesions, ...
European Parkinson's Disease Association
The European Parkinson's Disease Association (EPDA) is a non political, non-religious, and non-profit making organisation concerned with the health and welfare of people living with Parkinson's ...
The European Parkinson's Disease Association (EPDA) is a non political, non-religious, and non-profit making organisation concerned with the health and welfare of people living with Parkinson's ...
Fatal familial insomnia
Fatal familial insomnia is a very rare autosomal dominant inherited prion disease of the brain.
Fatal familial insomnia is a very rare autosomal dominant inherited prion disease of the brain.
Frontotemporal lobar degeneration
Frontotemporal lobar degeneration (FTLD) is the name for a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lo...
Frontotemporal lobar degeneration (FTLD) is the name for a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lo...
Huntington's disease
Huntington's disease is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and psychiatric problems.
Huntington's disease is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and psychiatric problems.
Infantile Refsum disease
Infantile Refsum disease (IRD), also called infantile phytanic acid storage disease, is a rare autosomal recessive congenital peroxisomal biogenesis disorder within the Zellweger spectrum.
Infantile Refsum disease (IRD), also called infantile phytanic acid storage disease, is a rare autosomal recessive congenital peroxisomal biogenesis disorder within the Zellweger spectrum.
Kennedy's disease
Kennedy's disease (KD) or X-linked Spinal and Bulbar Muscular Atrophy or Spinobulbar Muscular Atrophy (SBMA) or X-Linked Bulbo-Spinal Atrophy is an X-linked recessive, slow pro...
Kennedy's disease (KD) or X-linked Spinal and Bulbar Muscular Atrophy or Spinobulbar Muscular Atrophy (SBMA) or X-Linked Bulbo-Spinal Atrophy is an X-linked recessive, slow pro...
Krabbe disease
Krabbe disease is a rare, often fatal degenerative disorder that affects the myelin sheath of the nervous system.
Krabbe disease is a rare, often fatal degenerative disorder that affects the myelin sheath of the nervous system.
Lyme disease
Lyme disease, or Lyme borreliosis, is an emerging infectious disease caused by at least three species of bacteria belonging to the genus Borrelia.
Lyme disease, or Lyme borreliosis, is an emerging infectious disease caused by at least three species of bacteria belonging to the genus Borrelia.
Machado-Joseph disease
Machado–Joseph disease or Spinocerebellar ataxia type 3 is an extremely rare hereditary ataxia, which means a lack of muscle control.
Machado–Joseph disease or Spinocerebellar ataxia type 3 is an extremely rare hereditary ataxia, which means a lack of muscle control.
Machado–Joseph disease
Machado–Joseph disease (MJD) or Spinocerebellar ataxia type 3 (SCA3) is a rare autosomal, dominantly inherited neurodegenerative disease that causes progressive cerebellar ataxia, which re...
Machado–Joseph disease (MJD) or Spinocerebellar ataxia type 3 (SCA3) is a rare autosomal, dominantly inherited neurodegenerative disease that causes progressive cerebellar ataxia, which re...
Motor neurone disease
The motor neurone diseases or motor neuron diseases are a group of neurological disorders that selectively affect motor neurones, the cells that control voluntary muscle activity including...
The motor neurone diseases or motor neuron diseases are a group of neurological disorders that selectively affect motor neurones, the cells that control voluntary muscle activity including...
Multiple sclerosis
Multiple sclerosis is an inflammatory disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to demyelination and scarring as well as a broa...
Multiple sclerosis is an inflammatory disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to demyelination and scarring as well as a broa...
Neuroacanthocytosis
Neuroacanthocytosis is a term that refers to a group of genetically diverse conditions complicated by movement disorders, neurological problems and spiculated red blood cells.
Neuroacanthocytosis is a term that refers to a group of genetically diverse conditions complicated by movement disorders, neurological problems and spiculated red blood cells.
Niemann-Pick disease
Niemann–Pick disease (pronounced nē′mahn pik) refers to a group of fatal inherited metabolic disorders that are included in the larger family of lysosomal storage diseases (LSDs).
Niemann–Pick disease (pronounced nē′mahn pik) refers to a group of fatal inherited metabolic disorders that are included in the larger family of lysosomal storage diseases (LSDs).
Niemann–Pick disease
Niemann–Pick disease refers to a group of fatal inherited metabolic disorders that are included in the larger family of lysosomal storage diseases.
Niemann–Pick disease refers to a group of fatal inherited metabolic disorders that are included in the larger family of lysosomal storage diseases.
Pick's disease
Pick's disease is a rare neurodegenerative disease that causes progressive destruction of nerve cells in the brain.
Pick's disease is a rare neurodegenerative disease that causes progressive destruction of nerve cells in the brain.
Pontocerebellar hypoplasia
Pontocerebellar hypoplasia is a heterogeneous group of rare neurodegenerative disorders caused by genetic mutations and characterised by impaired development of various parts of the brain.
Pontocerebellar hypoplasia is a heterogeneous group of rare neurodegenerative disorders caused by genetic mutations and characterised by impaired development of various parts of the brain.
Primary lateral sclerosis
Primary lateral sclerosis is a rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles.
Primary lateral sclerosis is a rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles.
Progranulin
Progranulin (PGRN) is a protein which affects the human brain.
Progranulin (PGRN) is a protein which affects the human brain.
Progressive supranuclear palsy
Progressive supranuclear palsy is a degenerative disease involving the gradual deterioration and death of specific areas of the brain.
Progressive supranuclear palsy is a degenerative disease involving the gradual deterioration and death of specific areas of the brain.
Protein aggregation
Protein aggregation is a biological phenomenon in which mis-folded proteins aggregate either intra- or extracellularly.
Protein aggregation is a biological phenomenon in which mis-folded proteins aggregate either intra- or extracellularly.
Pyruvate dehydrogenase deficiency
Pyruvate Dehydrogenase Deficiency is one of the most common neurodegenerative disorders associated with abnormal mitochondrial metabolism.
Pyruvate Dehydrogenase Deficiency is one of the most common neurodegenerative disorders associated with abnormal mitochondrial metabolism.
Refsum disease
Refsum disease, also known as classic or adult Refsum disease, heredopathia atactica polyneuritiformis, phytanic acid oxidase deficiency and phytanic acid storage disease, is an autosomal recess...
Refsum disease, also known as classic or adult Refsum disease, heredopathia atactica polyneuritiformis, phytanic acid oxidase deficiency and phytanic acid storage disease, is an autosomal recess...
Sandhoff disease
Sandhoff disease, also known as Sandhoff-Jatzkewitz disease, variant 0 of GM2-Gangliosidosis or Hexosaminidase A and B deficiency, is a lysosomal genetic, lipid storage disorde...
Sandhoff disease, also known as Sandhoff-Jatzkewitz disease, variant 0 of GM2-Gangliosidosis or Hexosaminidase A and B deficiency, is a lysosomal genetic, lipid storage disorde...
Shy-Drager syndrome
Multiple system atrophy (MSA) is a degenerative neurological disorder.
Multiple system atrophy (MSA) is a degenerative neurological disorder.
Spinocerebellar ataxia
Spinocerebellar ataxia is a progressive, degenerative, genetic disease with multiple types, each of which could be considered a disease in its own right.
Spinocerebellar ataxia is a progressive, degenerative, genetic disease with multiple types, each of which could be considered a disease in its own right.
Subacute combined degeneration of spinal cord
Subacute combined degeneration of spinal cord, also known as Lichtheim's disease, refers to degeneration of the posterior and lateral columns of the spinal cord as a result of vitamin B12 de...
Subacute combined degeneration of spinal cord, also known as Lichtheim's disease, refers to degeneration of the posterior and lateral columns of the spinal cord as a result of vitamin B12 de...
Tay-Sachs disease
Tay–Sachs disease (abbreviated TSD, also known as GM2 gangliosidosis or Hexosaminidase A deficiency) is an autosomal recessive genetic disorder.
Tay–Sachs disease (abbreviated TSD, also known as GM2 gangliosidosis or Hexosaminidase A deficiency) is an autosomal recessive genetic disorder.
Tay–Sachs disease
Tay–Sachs disease is an autosomal recessive genetic disorder.
Tay–Sachs disease is an autosomal recessive genetic disorder.
Toxic encephalopathy
Toxic encephalopathy, also known as toxic-metabolic encephalopathy, is a degenerative neurologic disorder caused by exposure to toxic substances.
Toxic encephalopathy, also known as toxic-metabolic encephalopathy, is a degenerative neurologic disorder caused by exposure to toxic substances.
Transmissible spongiform encephalopathy
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a group of progressive conditions that affect the brain and nervous system of many animals, includ...
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a group of progressive conditions that affect the brain and nervous system of many animals, includ...
Variably protease-sensitive prionopathy
Variably protease-sensitive prionopathy (VPSPr) is a sporadic prion protein disease first described in 2010.
Variably protease-sensitive prionopathy (VPSPr) is a sporadic prion protein disease first described in 2010.
Wobbly hedgehog syndrome
Wobbly hedgehog syndrome is a disease found in the African Pygmy domesticated hedgehog.
Wobbly hedgehog syndrome is a disease found in the African Pygmy domesticated hedgehog.