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  1. pmc.ncbi.nlm.nih.gov

    Abstract Background and Aims. The gap between patients on transplant waiting lists and available donor organs is steadily increasing. Human organoids derived from leucine‐rich repeat‐containing G protein‐coupled receptor 5 (LGR5)-positive adult stem cells represent an exciting new cell source for liver regeneration; however, culturing large numbers of organoids with current protocols ...
    • Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem ...

      Background and aims: The gap between patients on transplant waiting lists and available donor organs is steadily increasing. Human organoids derived from leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5)-positive adult stem cells represent an exciting new cell source for liver regeneration; however, culturing large numbers of organoids with current protocols is tedious and the ...

  2. e-archivo.uc3m.es

    257 Hepatology, Vol. 72, No. 1, 2020 Liver injury/regeneration Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells Kerstin Schneeberger ,1 Natalia Sánchez-Romero,2* Shicheng Ye, 1* Frank G. van Steenbeek,1 Loes A. Oosterhoff,1 Iris Pla Palacin,2 Chen Chen,1,3 Monique E. van Wolferen,1 Gilles van Tienderen,1 Ruby Lieshout,4 Haaike Colemonts-Vroninks,5
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  4. researchgate.net

    Conclusions: We established a highly efficient method for culturing large numbers of LGR5-positive stem cells in the form of organoids, which paves the way for the application of organoids for ...
  5. pubmed.ncbi.nlm.nih.gov

    Background and aims: The gap between patients on transplant waiting lists and available donor organs is steadily increasing. Human organoids derived from leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5)-positive adult stem cells represent an exciting new cell source for liver regeneration; however, culturing large numbers of organoids with current protocols is tedious and the ...
    Author:Kerstin Schneeberger, Natalia Sánchez-Romero, Shicheng Ye, Frank G van Steenbeek, Loes A Oosterhoff,...Published:2020
  6. europepmc.org

    1 1 Large-scale Production of LGR5-positive Bipotential Human Liver Stem 2 Cells 3 4 5 Supplemental Experimental Procedures 6 7 Establishment of organoid cultures from liver tissue 8 Liver organoids were established in accordance with the ethical standards of the institutional 9 committee on human experimentation under the Erasmus MC license MEC 2014-060.
  7. researchinformation-acc.umcutrecht.nl

    Large-scale Production of LGR5-positive Bipotential Human Liver Stem Cells. Kerstin Schneeberger, Natalia Sánchez-Romero, Shicheng Ye, Frank G van Steenbeek, Loes A Oosterhoff, Iris Pla Palacin, Chen Chen, Monique E van Wolferen, Gilles van Tienderen, Ruby Lieshout, ...
  8. sigmaaldrich.com

    Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells. by Kerstin Schneeberger, Natalia Sánchez-Romero, Shicheng Ye, Frank G van Steenbeek, Loes A Oosterhoff, Iris Pla Palacin, Chen Chen, Monique E van Wolferen, Gilles van Tienderen, Ruby Lieshout, Haaike Colemonts-Vroninks, Imre Schene, Ruurdtje Hoekstra, Monique M A Verstegen, Luc J W van der Laan, Louis C Penning ...
  9. academia.edu

    BaCKgRoUND aND aIMS: The gap between patients on transplant waiting lists and available donor organs is steadily increasing. Human organoids derived from leucine-rich repeatcontaining G protein-coupled receptor 5 (LGR5)-positive adult stem cells represent an exciting new cell source for liver regeneration; however, culturing large numbers of organoids with current protocols is tedious and the ...
  10. Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells K Schneeberger, N Sánchez-Romero, S Ye, FG van Steenbeek, LA Oosterhoff, I Pla Palacin, C Chen, ME van Wolferen, G van Tienderen, Ruby Lieshout, H Colemonts-Vroninks, I Schene, R Hoekstra, Monique Verstegen , Luc van der Laan , LC Penning, SA Fuchs, H Clevers, J De Kock ...

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