Always private
DuckDuckGo never tracks your searches.
Learn More
You can hide this reminder in Search Settings
All regions
Argentina
Australia
Austria
Belgium (fr)
Belgium (nl)
Brazil
Bulgaria
Canada (en)
Canada (fr)
Catalonia
Chile
China
Colombia
Croatia
Czech Republic
Denmark
Estonia
Finland
France
Germany
Greece
Hong Kong
Hungary
Iceland
India (en)
Indonesia (en)
Ireland
Israel (en)
Italy
Japan
Korea
Latvia
Lithuania
Malaysia (en)
Mexico
Netherlands
New Zealand
Norway
Pakistan (en)
Peru
Philippines (en)
Poland
Portugal
Romania
Russia
Saudi Arabia
Singapore
Slovakia
Slovenia
South Africa
Spain (ca)
Spain (es)
Sweden
Switzerland (de)
Switzerland (fr)
Taiwan
Thailand (en)
Turkey
Ukraine
United Kingdom
US (English)
US (Spanish)
Vietnam (en)
Safe search: moderate
Strict
Moderate
Off
Any time
Any time
Past day
Past week
Past month
Past year
  1. organtrans.eu

    This deliverable, 1.1 "six established and fully characterized individual hepatic organoid lines", part of work package 1 (WP1), reports the establishment of six hepatic cell lines. The overall aim of WP1, Stem cell source and requirements, is to create standardized liver spheroids with hepatic function and tissue architecture.
    • Results

      D1.1 Six established and fully characterized individual hepatic organoid lines D1.2 Protocol for the large-scale production of liver organoids D2.2 Upscaling from research to medical Sphericalplate 5D D7.4 Sensor for the monitoring of dissolved oxygen D9.1 Dissemination and communication strategy D9.2 Project webpage

  2. organtrans.eu

    ORGANTRANS WP1, D1.2, V1.0 Page 7 of 8 FIG. 2. Enhanced liver organoid expansion in spinner flasks. Spinner flasks were inoculated with 2.5 × 106 single organoid cells (105 cells/mL) at day 0 and cultured in human organoid EM supplemented with the Rho kinase inhibitor Y27632 and 10% vol/vol Matrigel; 4-5 different donors were analyzed in ...
  3. Jan 31, 2024New tissue engineering and 3D printing techniques could transform how liver disease is treated, potentially saving thousands of lives. The results of the EU-H2020 funded ORGANTRANS project, set to develop a disruptive solution that enables the 3D printing of tissue-engineered constructs, have been published in six languages on EU-Cordis Database.
  4. pmc.ncbi.nlm.nih.gov

    To fully recapitulate liver physiology and function using hPSCs may require a mixed population of hepatic cells, which exhibit the correct polarity and arrangement in a 3D context. ... The Ouchi et al. hepatic organoid model shows the advantages of HSCs in an organotypic setting that in combination with Kupffer cells, the resident liver ...
  5. Was this helpful?
  6. stemcellres.biomedcentral.com

    Aug 7, 2024The liver is the most important metabolic organ in the body. While mouse models and cell lines have further deepened our understanding of liver biology and related diseases, they are flawed in replicating key aspects of human liver tissue, particularly its complex structure and metabolic functions. The organoid model represents a major breakthrough in cell biology that revolutionized ...
  7. pmc.ncbi.nlm.nih.gov

    Organoid therapy may be a powerful adjunctive or alternative to deceased donor or living donor liver transplantation in the future because of its ability to suppress liver damage. This therapy may be effective for the recipient of liver transplantation, or patients who are ineligible for liver transplantation, or even as organ preservation in ...
  8. ncbi.nlm.nih.gov

    National Center for Biotechnology Information

    https://www.ncbi.nlm.nih.gov › pmc › articles › PMC7683012

    Biobanks of human liver cell lines and organoids have been established and would be enlarged with high expectations for testing efficacy and toxicity of drugs in clinical studies and personalized medicine, as they harbored the possibility to reflect features of human liver tissues, including basic functions and certain heterogeneities (Qiu et ...
  9. cordis.europa.eu

    Nov 17, 2023The ORGANTRANS project has helped to build up European expertise in tissue engineering, and established liver grafts as a viable future therapy. To make this a reality, the gap between successful lab research and commercialisation must now be bridged. This will require pharma industry involvement, and further research funding.
  10. pmc.ncbi.nlm.nih.gov

    Human Liver Organoid Cultures. For the establishment of liver organoids, liver tissue samples were obtained from the normal margins surrounding tumor tissue from three individual donors. The BCM Institutional Review Board approved the study protocol to obtain tissue samples from which the liver organoid lines were derived.

    Can’t find what you’re looking for?

    Help us improve DuckDuckGo searches with your feedback

Custom date rangeX