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  1. ncbi.nlm.nih.gov

    National Center for Biotechnology Information

    https://www.ncbi.nlm.nih.gov › pmc › articles › PMC7239030

    Streptococcus suis. is a Gram-positive bacterium and zoonotic pathogen that causes meningitis and sepsis in pigs and humans. The aim of this study was to identify genes required for S. suis infection. We created Tn-Seq libraries in a virulent S. suis strain 10, which was used to inoculate pigs in an intrathecal experimental infection. Comparative analysis of the relative abundance of mutants ...
    Publication:Virulence. 2020; 11(1): 446-464.Author:Jesús Arenas, Aldert Zomer, Aldert Zomer, Jose Harders-Westerveen, Hester J Bootsma, Marien I De Jon...Published:2020
  2. sciencedirect.com

    In this paper, we report development of a novel STM analysis method using the Luminex xMAP ... Evaluation of individual candidate mutants for virulence in CDCD pigs. To determine attenuation in the natural porcine host, 14 mutants from the original mouse screen and 8 mutants from the pig screen were evaluated individually for virulence in CDCD ...
    Author:Thomas L. Wilson, Jenifer Jeffers, Vicki J. Rapp-Gabrielson, Stephen Martin, Loretta K. Klein, David...Published:2007
  3. ncbi.nlm.nih.gov

    National Center for Biotechnology Information

    https://www.ncbi.nlm.nih.gov › pmc › articles › PMC9143085

    1. Introduction. Streptococcus suis (S. suis) is an important zoonotic pathogen causing serious diseases in pigs, including meningitis, endocarditis, and sepsis, and can also infect humans, leading to streptococcal toxic shock-like syndrome (STSLS) and even acute death [1,2,3].Serotype 2 (SS2) is the most virulent and prevalent serotype in pigs and human beings among the numerous (at least 29 ...
    Publication:Microorganisms. 2022 May; 10(5): 868.
  4. ncbi.nlm.nih.gov

    National Center for Biotechnology Information

    https://www.ncbi.nlm.nih.gov › pmc › articles › PMC7564649

    Streptococcus suis (S.suis) is an important zoonotic pathogen that causes many severe diseases in pigs and humans.Virulence-related transcriptional regulators have been widely reported in pathogenic microorganisms, but only a few have been identified in S.suis.Our aim was to screen virulence-related transcriptional regulators in S.suis.A total of 89 such genes were predicted in the S.suis ...
    Publication:Genes (Basel). 2020 Sep; 11(9): 972.Author:Liang Liu, Qiang Zhang, Zhongmin Xu, Bo Chen, Anding Zhang, Xiaomei Sun, Meilin JinPublished:2020
  5. sciencedirect.com

    In this report, the role of this selected transcription regulator (Tran) in the pathogenesis of an S. suis infection was studied. Microarray analysis was performed to identify gene transcription profiles using tran knock-out mutant compared to the wild-type strain ZY05719, which was originally isolated from SS2 infected pigs in Sichuan province by our group in 2005 (Chen et al., 2007).
  6. pmc.ncbi.nlm.nih.gov

    Abstract. Streptococcus suis is ubiquitous in swine, and yet, only a small percentage of pigs become clinically ill. The objective of this study was to describe the distribution of serotypes, virulence-associated factor (VAF), and antimicrobial resistance (AMR) genes in S. suis isolates recovered from systemic (blood, meninges, spleen, and lymph node) and non-systemic (tonsil, nasal cavities ...
  7. pubmed.ncbi.nlm.nih.gov

    Streptococcus suis (S. suis) is a zoonotic bacterial pathogen causing lethal infections in pigs and humans. Identification of virulence-related genes (VRGs) is of great importance in understanding the pathobiology of a bacterial pathogen. To identify novel VRGs, a transposon (Tn) mutant library of S. suis strain SC19 was constructed in this ...
  8. researchgate.net

    Streptococcus suis (S. suis) is a zoonotic bacterial pathogen causing lethal infections in pigs and humans. Identification of virulence-related genes (VRGs) is of great importance in understanding ...
  9. pubmed.ncbi.nlm.nih.gov

    Streptococcus suis is a Gram-positive bacterium and zoonotic pathogen that causes meningitis and sepsis in pigs and humans. The aim of this study was to identify genes required for S. suis infection. We created Tn-Seq libraries in a virulent S. suis strain 10, which was used to inoculate pigs in an intrathecal experimental infection. Comparative analysis of the relative abundance of mutants ...

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