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Showing results excluding:
  • pmsmattrain.eu

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  1. curamdevices.ie

    PMSMatTrain focuses on gaining a comprehensive understanding of the progressive phase of multiple sclerosis (PMS) from basics to translation, fully supported by eight beneficiaries (six research institutions and two SMEs).
  2. ncbi.nlm.nih.gov

    National Center for Biotechnology Information

    https://www.ncbi.nlm.nih.gov › pmc › articles › PMC8911110

    Therefore, a single molecular marker is unlikely to exist, and efforts on molecular research in multiple sclerosis should be made towards integrating analytic approaches, including clinical characteristics, MRI variables and proteins, and metabolite concentrations to create signatures of MS disease diagnosis, prognosis, and treatment response.
  3. pmc.ncbi.nlm.nih.gov

    The etiology of multiple sclerosis (MS) is not clear, and the treatment of MS presents a great challenge. This study aimed to investigate the pathogenesis and potential therapeutic targets of MS and to define target genes of matrine, a quinolizidine ...
  4. pmc.ncbi.nlm.nih.gov

    Abstract Multiple sclerosis (MS) is a chronic inflammatory disease characterized by central nervous system (CNS) lesions that can lead to severe physical or cognitive disability as well as neurological defects. Although the etiology and pathogenesis of MS remains unclear, the present documents illustrate that the cause of MS is multifactorial and include genetic predisposition together with ...
  5. cordis.europa.eu

    Oct 28, 2024Wiley 10.1002/glia.24419 Molecular Mechanisms of Physiological and Pathophysiological Processes inMultiple Sclerosis-like Models Ex Vivo and In Vivo Maurine Fucito European Neuroscience Conference by Doctoral Students-Posters, 2021, Page (s) P6A25 Brain Proteomic Signatures of an in vivo Model of Multiple Sclerosis
  6. ncbi.nlm.nih.gov

    National Center for Biotechnology Information

    https://www.ncbi.nlm.nih.gov › pmc › articles › PMC5743213

    Therefore, using multiple sclerosis (MS) as an example of a complex polygenic neurological disease, we sought to determine if cerebrospinal fluid (CSF) biomarkers are intra-individually stable, cell type-, disease- and/or process-specific and responsive to therapeutic intervention.
  7. pubmed.ncbi.nlm.nih.gov

    Sep 15, 2023Background: Multiple sclerosis (MS), a chronic inflammatory disorder, affects the central nervous system via myelin degradation. The cause of MS is not fully known, but during recent years, our knowledge has deepened significantly regarding the different aspects of MS, including etiology, molecular pathophysiology, diagnosis and therapeutic ...
  8. pubmed.ncbi.nlm.nih.gov

    Nov 4, 2024Recent advancements in research have significantly enhanced our comprehension of the intricate immune components that contribute to multiple sclerosis (MS) pathogenesis. By conducting an in-depth analysis of complex molecular interactions involved in the immunological cascade of the disease, researchers have successfully identified novel therapeutic targets, leading to the development of ...

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