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  1. sciencedirect.com

    In 2008, the seminal work by Ott and coworkers, who successfully generated whole rat acellular hearts by means of perfusion decellularization, represented a breakthrough in the field of tissue engineering and the beginning of the era of whole organ decellularization technology [36].Over the last years, different research groups following similar approaches have reported the possibility to ...
    • Sequences and Domain Structures of Mammalian, Avian, Amphibian and Teleost Tropoelastins

      The general arrangement of alternating hydrophobic and crosslinking domains that is a prominent characteristic of human, mouse and chicken tropoelastins (Fig. 4) is also clearly present in tropoelastins from zebrafish and xenopus (Fig. 5).In most cases domains correspond to exons, such that designations of exons as either hydrophobic or crosslinking are straightforward.

    • Local Micromechanical Properties of Decellularized Lung Scaffolds Measured With Atomic Force Microscopy

      Mechanical properties of acellular lung tissue have been probed in air-filled decellularized murine lungs by recording quasi-static pressure-volume curves during inflation and deflation [34] and by measuring respiratory impedance with the forced oscillation technique [46].This approach does not provide accurate estimation of lung parenchymal ECM, since mechanical measurements performed on ...

    • Matrix Preparation, Reseeding Technique and Short-Term Implantation in a Porcine Model

      Reconstruction of the urinary tract using the principles of tissue engineering has been a major focus of experimental research in latter years. 1 Different acellular matrices or scaffolds reseeded with viable cells are the 2 main options for this kind of tissue replacement. In each case the ideal matrix should be biocompatible, bioabsorbable, nonimmunogenic and able to support cell attachment ...

    • Bioreactor Design for Perfusion-Based, Highly Vascularized Organ Regeneration

      The premise of bioartificial organs is to strip an organ that is nontransplantable, due to parenchyma scarring or high fat content, of its cellular components using a process termed decellularization to yield a scaffold on which to develop a new organ (Figure 1).Important properties of these scaffolds are retention of native tissue architecture and maintenance of extracellular matrix (ECM ...

    • Three-Dimensional Filamentous Human Diseased Cardiac Tissue Model

      A human in vitro cardiac tissue model would be a significant advancement for understanding, studying, and developing new strategies for treating cardiac arrhythmias and related cardiovascular diseases. We developed an in vitro model of three-dimensional (3D) human cardiac tissue by populating synthetic filamentous matrices with cardiomyocytes derived from healthy wild-type volunteer (WT) and ...

  2. diposit.ub.edu

    (3D) bioprinting advancements (reviewed in [10-13]). Current 3D bioprinting techniques have shown to simultaneously de-posit combinations of different cell types encapsulated within biomimetichydrogels via a layer-by-layerprocess, leadingto the generation of 3D bioinspired tissue constructs (reviewed in [10,12,14,15]) [16-20].
  3. semanticscholar.org

    DOI: 10.1016/J.MATTOD.2016.12.005 Corpus ID: 35122158; Tissue engineering by decellularization and 3D bioprinting @article{Garreta2017TissueEB, title={Tissue engineering by decellularization and 3D bioprinting}, author={Elena Garreta and Roger Oria and Carolina Tarantino and Mateu Pla-Roca and Patricia Prado and Francisco Fern{\'a}ndez‐Avil{\'e}s and Josep M Campistol and Josep Samitier and ...
  4. pmc.ncbi.nlm.nih.gov

    Three-dimensional (3D) bioprinting is a form of tissue engineering approach using additive manufacturing that employs 3D imaging modalities and computer-aided design software to three-dimensionally bioprint tissues and organs layer by layer using a plethora of biomaterials in a customized and specific pattern .
  5. ncbi.nlm.nih.gov

    Decellularization of tissue and 3D bioprinting of tissue-like constructs have potential to achieve solid organs ex vivo, but each is executed in a completely different fashion. Here, we compare these two technologies such that they might be most appropriately applied to a given tissue-type or regenerative medicine application (Table 1 ).
  6. pubs.acs.org

    Decellularization and Their Significancefor Tissue Regeneration in the Era of 3D Bioprinting Mrunmayi Gadre, Meghana Kasturi, Prachi Agarwal, and Kirthanashri S. Vasanthan* ... tissue engineering and regenerative medicine. Increasing advancement and improvement in the decellularization process have led to an increase in the demand for using a ...
  7. pmc.ncbi.nlm.nih.gov

    The classical approaches to tissue engineering. Reproduced under open access from [], published by MDPI, 2019.Tissue engineering and regenerative medicine (TERM) is the integration of medicine and bioengineering, which has resulted in the two having become widely interchangeable terms, as both fields focus on restoring tissue functionality to the body [3,6].
  8. sciencedirect.com

    Decellularized extracellular matrix (dECM) is a highly attractive biomaterial used in the field of bioprinting for creating engineered living materials [1] and tissue constructs [2].In the realm of regenerative medicine, bioprinting human tissues using eukaryotic cells and matrices from mammal origin is particularly important. dECM plays a crucial role by mimicking the composition structure of ...
  9. pubs.acs.org

    Three-dimensional bioprinting is an emerging technology that has high potential application in tissue engineering and regenerative medicine. Increasing advancement and improvement in the decellularization process have led to an increase in the demand for using a decellularized extracellular matrix (dECM) to fabricate tissue engineered products. Decellularization is the process of retaining the ...
  10. researchgate.net

    Tissue engineering by decellularization and 3D bioprinting. January 2017; Materials ... three-dimensional (3D) bioprinting techniques are advancing towards the fabrication of biomimetic cell-laden ...

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