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  1. However, this is not a setback but rather an advantage. In this project, we will use the pleiotropies that involve teeth to open windows to the evolution of human anatomies far beyond the dentition. We employ three methodological approaches that utilize pleiotropy to probe different aspects of human paleobiology.
  2. cordis.europa.eu

    Teeth dominate the fossil and bioarchaeological records because they consist mostly of inorganic material. Consequently, dental anthropology has long been essential in our investigation of the human past. Variation in the anatomy of teeth is instrumental for differentiating...
  3. Dr. Leslea Hlusko is the Lead Researcher (henceforth, "IP") of the project Tied2Teeth: "Expanding our understanding of human evolution through pleiotropy" whose objective is to study the influence of the genes acting on dental variation upon aspects of human anatomy, and to apply this to the fossil record of the Iberian Peninsula and eastern Africa.
  4. lesleahlusko.org

    Tied2Teeth is a European Research Council Advanced Grant project hosted by the CENIEH funded through the 2021 call for applications. Financial support is provided from 1 November 2022 through October 2027. Follow on Twitter @Tied2Teeth. Employment opportunities: We will soon be searching for two technicians to assist with data entry and data collection. . The calls will be posted on the CENIEH ...
  5. euraxess.ec.europa.eu

    Jun 13, 2023Ref: 04/2023 ERC-2021-ADG TIED2TEETH. General guidelines. Dr. Leslea Hlusko is the Lead Researcher (henceforth, "PI") of the project TIED2TEETH: "Expanding our understanding of human evolution through pleiotropy" whose objective is to study the influence of the genes acting on dental variation upon aspects of human anatomy, and to apply this to the fossil record of the Iberian Peninsula ...
  6. lesleahlusko.org

    Title: Expanding our understanding of human evolution through pleiotropy (Tied2Teeth) Project 101054659-Tied2Teeth- ERC-2021-ADG . PI: LJ Hlusko . 2021 National Science Foundation ($585,301) 2021-2024 . Title: Disentangling the genetic, biomechanical, and deep-time factors underlying mammalian
  7. pmc.ncbi.nlm.nih.gov

    The consequences of pleiotropy for evolution (i.e., its effects on evolvability) have also been debated. 21,59,68,69 Several authors have proposed that highly multivariate phenomic data, analyzed in a formal multivariate framework, are necessary to determine both the prevalence of pleiotropy and the extent to which it constrains evolution. 66 ...
  8. developmentaid.org

    Reference — Expanding Our Understanding of Human Evolution Through Pleiotropy: Tied2Teeth — for Spain presented by Horizon Europe (2021 - 2027) (grants), budget is EUR 2252167, in Health, Research, Science & Innovation sectors. Reference — Expanding Our Understanding of Human Evolution Through Pleiotropy: Tied2Teeth — for Spain ...
  9. Ref: 05/2023 ERC-2021-ADG TIED2TEETH 1. General guidelines Dr. Leslea Hlusko is the Lead Researcher (henceforth, "PI") of the project Tied2Teeth: "Expanding our understanding of human evolution through pleiotropy" whose objective is to study the influence of the genes acting on dental variation upon aspects of human
  10. pmc.ncbi.nlm.nih.gov

    Beyond providing context for existing analyses and treatments, new approaches are needed to translate our understanding of the history of human evolution from basic research to clinical relevance. In the main text, we highlight examples of how trade-offs, caused by competition for resources or antagonistic pleiotropy, may produce contrasting ...

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