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  1. Was this helpful?
  2. ncbi.nlm.nih.gov

    Megahertz serial crystallography. Pulses from the European XFEL were focused on the interaction region using a set of Beryllium lenses. ... (2014-2018); the Gottfried Wilhelm Leibniz Program of the DFG; the project "X-probe" funded by the European Union's 2020 Research and Innovation Program under the Marie Sklodowska-Curie grant ...
  3. ncbi.nlm.nih.gov

    The advent of Serial Femtosecond Crystallography (SFX) has created opportunities via which macromolecular structures can be probed and their dynamics investigated. SFX is ideally suited to studying the molecular dynamics of molecules undergoing irreversible processes which cannot be measured using conventional synchrotron or lab-based X-ray ...
  4. ncbi.nlm.nih.gov

    The European XFEL does not deliver a uniform stream of X-ray pulses, rather it delivers 10 bursts (trains) of X-ray pulses/second with each burst containing up to 2700 X-ray pulses at an interpulse repetition rate of up to 4.5 MHz (1.1 MHz in this experiment), Fig. 1. The megahertz intrabunch repetition rate of the European XFEL poses unique ...
  5. sciencedirect.com

    Serial femtosecond X-ray crystallography has emerged as a powerful method for investigating biomolecular structure and dynamics. With the new generation of X-ray free-electron lasers, which generate ultrabright X-ray pulses at megahertz repetition rates, we can now rapidly probe ultrafast conformational changes and charge movement in biomolecules.
  6. link.aps.org

    Observation of shock-induced protein crystal damage during megahertz serial femtosecond crystallography Marie L. Grünbein et al. ... The first pulse (pump) launches a shock that passes through the crystals probed by the second pulse (probe) 8.4 or 122.5 ns later. The photon energies of the pulses are different and chosen such that only the x ...
  7. ncbi.nlm.nih.gov

    The results indicate the feasibility for megahertz serial crystallography measurements with hard X-rays and give guidance for the design of such experiments. Keywords: X-ray free-electron lasers, ... with an increased sampling of time delays below 100 ns in order to probe the fast dynamics during the onset of the jet explosion. We further ...

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