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  1. Aug 21, 2024Electrolyte-gated organic transistors are ultrasensitive label-free biosensors. By exploiting this sensitivity, Manco Urbina et al. characterize the analyte binding kinetics on the sensor surface by real-time monitoring of the sensor response. The analysis of this response allowed them to detect small variations in the binding site affinities on the electrode surface.
  2. pubs.acs.org

    Explicit antigen-antibody binding has accelerated the development of immunosensors for the detection of various analytes in biomedical and environmental domains. Being a subclass of biosensors, immunosensors have been a significant area of research in attaining high sensitivity and an ultralow sensing limit to detect biological analytes present in trace levels. The highly porous structure ...
  3. Chemogenetics for sensing antigens Cell Research ( IF 28.1) Pub Date : 2025-01-15, DOI: 10.1038/s41422-025-01072- Blake A. Fordyce, Bryan L. Roth Antigen-based systems offer highly specific binding and customizability, broadening their application to various fields of cell biology.
  4. pubmed.ncbi.nlm.nih.gov

    Oct 4, 2024Three different strategies for constructing input sequence alignments are employed for predicting structural models of antigen-antibody complexes. In our initial testing set, which comprises known experimental structures, these strategies collectively yield a significant top-ranked prediction for 61% of cases and a success rate of 47%.

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