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  1. pmc.ncbi.nlm.nih.gov

    The immune response to the vaccines was worse in the elderly than in the younger population. In 6 studies that compared single-dose and double-dose vaccination, 4 studies showed that double-dose vaccination produced a stronger immune response than single-dose vaccination. Conclusions Most of the COVID-19 vaccines appear to be effective and safe.
  2. scientificamerican.com

    There is no question that the current vaccines are effective and safe. The risk of severe reaction to a COVID-19 jab, say researchers, is outweighed by the protection it offers against the deadly ...
  3. Work is continuing While all data points to COVID-19 vaccines being both safe and effective, work on monitoring the vaccines continues. The Food and Drug Administration (FDA), CDC, researchers and developers are continuing to gather information about the safety and efficacy of COVID-19 vaccines. "The science is not stopping," Hoffman said.
  4. pmc.ncbi.nlm.nih.gov

    Regarding the interchangeability of COVID-19 vaccines, the WHO recommends using the same COVID-19 vaccine for both doses of a two-dose schedule 27, but there is scientific evidence of the effectiveness of heterologous vaccination with AstraZeneca or Covishield as the first dose and an mRNA vaccine as the second dose 28, 29, 30.
  5. pmc.ncbi.nlm.nih.gov

    Aluminum-adjuvanted vaccines had the lowest systemic and local side effects between vaccines' adjuvant or without adjuvant, except for injection site redness. The adenovirus-vectored and mRNA-based vaccines for COVID-19 showed the highest efficacy after first and second doses, respectively. The mRNA-based vaccines had higher side effects.
  6. World Health Organization (WHO) has added Pfizer-BioNTech, Moderna, Sinovac, Sinopharm-BBIBP, Oxford-AstraZeneca and Janssen to list of safe and effective emergency tools against COVID-19. However, these vaccines lack effective evaluation in people with underlying medical conditions.
  7. news.cornell.edu

    COVID-19 vaccines, proven to be extremely safe, are effective at protecting the public in two ways: They shield most individuals from getting sick; and they reduce the chance that people will transmit the virus to others. This was among the key messages relayed during "The Science Behind COVID-19 Vaccines," a virtual Q&A-style panel discussion held April 12 with Cornell immunology experts ...
  8. templehealth.org

    But the fast timeline has raised questions about whether the vaccines are safe and if they were tested long enough. As a researcher who studies viral infections, I'll explain the science behind the vaccines and why they're safe and effective. How are the first COVID-19 vaccines different from most other vaccines?
  9. The elderly and people with comorbidities are at greatest risk of severe coronavirus disease 2019 (COVID-19). A safe and effective vaccine could help to protect these groups in two distinct ways: direct protection, where high-risk groups are vaccinated to prevent disease, and indirect protection, where those in contact with high-risk individuals are vaccinated to reduce transmission. Influenza ...
  10. Sep 10, 2024What CDC is doing Results of vaccine effectiveness studies are critical to CDC's vaccine program and national vaccine policy decision-making. The overall goal of CDC's vaccine effectiveness program is to generate the comprehensive evidence needed to inform COVID-19 vaccine policy decisions and CDC guidance on other prevention measures.

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